Toxicokinetics of paraquat in Korean patients with acute poisoning
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چکیده
منابع مشابه
Toxicokinetics of paraquat in Korean patients with acute poisoning
To conduct a kinetic study of paraquat (PQ), we investigated 9 patients with acute PQ intoxication. All of them ingested more than 20 ml of undiluted PQ herbicide to commit suicide and arrived at our hospital early, not later than 7 h after PQ ingestion. The urine dithionite test for PQ in all of the nine patients was strongly positive at emergency room. Blood samples were obtained every 30 min...
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Paraquat poisoning is very severe. Most victims, including those who have ingested a small amount, will die from Paraquat poisoning. The cause of death in the majority of such cases is lung fibrosis. Paraquat poisoning in patients with positive human immunodeficiency virus (HIV) infection status has seldom been reported. Herein, we report a case of an HIV patient with Paraquat poisoning who had...
متن کاملMetabolic Profiling of Amino Acids Associated with Mortality in Patients with Acute Paraquat Poisoning
BACKGROUND Paraquat is a major cause of fatal poisoning after ingestion in many parts of Asia and the Pacific nations. However, optimal prognostic indicators to evaluate patient mortality have not been unequivocally established. Following acute paraquat poisoning, a number of amino acids (AA), are abnormally expressed in metabolic pathways. However, the alterations in AA metabolite levels after...
متن کاملThe Value of Plasma Paraquat Concentration in Predicting Therapeutic Effects of Haemoperfusion in Patients with Acute Paraquat Poisoning
OBJECTIVE This study was aimed to analyze the scavenging effect of haemoperfusion on plasma paraquat (PQ) and to evaluate the clinical significance of PQ examination in the treatment of patients with acute paraquat poisoning. METHODS 85 patients with acute paraquat intoxication by oral ingestion were admitted in West China Hospital from Jun, 2010 to Mar, 2011. A standardized therapeutic regim...
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ژورنال
عنوان ژورنال: The Korean Journal of Physiology & Pharmacology
سال: 2016
ISSN: 1226-4512,2093-3827
DOI: 10.4196/kjpp.2016.20.1.35